What are the chances that the fetus will be malformed if you have an ongoing pregnancy?
If you have an ongoing pregnancy after using Misoprostol, the risk of having a baby with fetal malformations is increased. However, this risk is very small, less than 1 in 1000. This risk is smaller than the normal risk of having a baby with Down Syndrome.
If possible, we advise women with ongoing pregnancies to undergo surgical or medical abortions to terminate the pregnancy in order to entirely avoid the risk of having a malformed fetus.
More scientific info:
Research suggests that a fetus that has been exposed to Mifepristone alone and is not aborted will continue to develop normally 26 . Exposure of fetuses to Misoprostol can lead to malformations, such as defects in the skull and abnormalities in the limbs (called Mobius Syndrome) 59 . However, risk of having a baby with malformations after using Misoprostol is still very small and hardly measurable. “ 47 .
To compare: the risk of having a child with Down syndrome is 1/1,300 for a 25-year-old woman; at age 35, the risk increases to 1/365. 52 Only pregnant women older than 35 are screened for Down Syndrome indicating that the risk that the fetus has down Syndrome lower than 1 in 365 is considered acceptable. This is a much higher risk than the risk of Mobius Syndrome as a result of the use of Misoprostol (less than 1/1000).
Because of restrictions on the distribution of Mifepristone, many women currently must use Misoprostol alone, even though it is less effective. By making a more effective regimen available, this abortion help service makes the home medical abortion procedure safer for women and reduces the chance that pregnancies will continue and result in the births of malformed infants, even if the risk is very small.